A postdoc position in a project to develop a diagnostic biomarker assay for rheumatoid arthritis is now open. It is placed at Southern Medical University, Guangzhou, China and the research will be performed at both SMU and at Karolinska Institutet, Stockholm, Sweden.
Form of employment:
Full-time, 3 years (with a trial employment for 6 months) and with a possibility of prolongation.
Start: as soon as possible.
Apply before: Nov 23, 2015.
Description:
Applications are invited for a position as a postdoc in a project led by Prof. Rikard Holmdahl. The task is to develop multiplex assays for detection of antibodies to defined protein epitopes and to analyse both experimental animal models and human samples.
Project:
The project aims to develop a diagnostic test for rheumatoid arthrtitis. The test is based on unique antigenic epitopes derived from various joint proteins. The epitopes has been formulate as conformational peptides but needs to be further improved regarding their functional and diagnostic role. As these peptides and epitopes are shared between mice and humans that are possibilities to make in depth functional analysis in the mouse as well as testing of human sera for assay development. The assay development will be developed using a multiplex platform, and also analyzed in detail regarding their physical properties. Thus solid-phase assays using ELISA will be compared with multiplex platforms using other technologies, one of them based on a Luminex platform. The project involve both in depth analyses and the coordination of large cohorts. This includes analyses with advanced statistical methods. Besides the laboratory work the position will also involve coordination of the project with participating clinicians in both China and Europe. The goal is to develop a suitable diagnostic test and to publish the results in leading international journals.
Qualifications:
To qualify, the applicant must hold a PhD in medicine or biological science. Fluent English is an absolute requirement as the lab working language is English. Easiness with social communication are requirements. Computer skills, bioinformatics knowledge and statistical analysis are needed. Laboratory experience and excellence is a requirement.
Contact and Application:
Apply directly to Angel Yao Mattisson (Angel.Yao-Mattisson@ki.se). Please mention the job number (MIR-1503) in your application.
Medical Inflammation Research (MIR) 