Current Vacant Positions
(updated 24th September 2015)
Postdoc in experimental immunology (MIR-1501) – International recruitment
Postdoc in biochemistry (MIR-1502) – International recruitment
Postdoc in bioinformatics (MIR-1503) – International recruitment
Previously announced and completed positions
Scientist Position in Medical Inflammation Research
Applications are invited for a scientist position in the Medical Inflammation Research division, Department of Medical Biochemistry and Biophysics
A scientist position is open now for a highly motivated person with a strong background in immunology and mouse genetics. She/he should have a wide practical experience with inflammatory disease models. The senior researcher will explore the disease pathways involved in several autoimmune diseases using experimental arthritis, psoriasis and lupus models.
For details, visit this URL and apply through the link given in that page.
Postdoctoral position in immunology of inflammatory disease
For investigating atherosclerosis and inflammatory pathways in mice with genes identified to control arthritis, at the CERIC Linné Center, Karolinska Institutet. The Center for Research on Inflammation and Cardiovascular Disease (CERIC) is a new Linné center (http://www.ceric.se) funded by the Swedish Research Council. A postdoc position is now open for a highly motivated scientist with an interest in understanding how the immune system contributes to development of cardiovascular disease. For further information contact Prof Rikard Holmdahl, Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet.
For details, visit this URL and apply through the link given in that page.
PhD Position to study functional genetics of new genes regulating inflammation and arthritis We are looking for a motivated student to work in a research project on the regulation of experimental arthritis in both rat and mouse. The student will be working on a research project aiming to unravel the functional role of 2 newly positioned genes controlling autoimmune arthritis in mice. Congneic strains with these genes isolated in very small fragment, both of them are regarded as positional cloned, are available. This has not yet been published but awaits a functional analysis understanding their mechanistic role in the inflammatory process. Both of the genes seem to be involved in macrophage regulation and one of them regulated by sex steroids. The associated pathways will involve a broad set of in vitro and in vivo technologies. Since the project aims to understand the function of a gene and how it is regulated it is important that the student is interested in learning and mastering many different techniques as well as having an inquisitive and methodical approach. The project will include both in vitro and in vivo studies, and the student will be trained in both cellular and molecular techniques to identify important pathways and interactors. A large focus will be on phenotype assessment of genetically engineered mice that will be crossed with the congenic strains to elucidate the pathways of interest. The student will work directly with Professor Rikard Holmdahl.
For details, visit this URL and apply through the link given in that page.
Doctoral student position in experimental arthritis
A PhD position is available funded by Karolinska Institute KID grant. We are looking for a highly motivated and inquisitive person. This fellow candidate will work with Dr. Kutty Selva Nandakumar, Associate Professor at the section of Medical Inflammation Research. The PhD project is focused on investigating how estrogen affects antibody synthesis, glycosylation and effector functions in arthritis. The project entails work on the cartilage biochemistry, cell biology, genetics, histopathology, experimental mouse work, molecular biology, epigenetics, and antibody recognition of protein(s). The project includes breeding, maintaining and using of transgenic and congenic mouse strains. The candidate should be self-motivated with good communication skills and an ability to interact effectively and work productively in a team. Emphasis will be placed on personal suitability. Fluency in English is a requirement. This PhD project is planned to last four years + 6-month trial period starting in 2014.
PhD Position within regulation of chronic inflammation by C-type lectin receptors
Project description: C-type lectins are a family of receptors expressed on antigen presenting cells and are involved in many processes of innate immunity such as pattern recognition of pathogens, cytokine production, and antigen uptake. We are looking for a motivated student to work in a research project on the regulation of experimental arthritis in both rat and mouse. The main focus will be on receptor-mediated activation of innate immunity and how this activation contributes to the development of autoimmune T cells and experimental arthritis. The student will be working on a research project aiming to characterize the function of two C-type lectin receptors. By genetic dissection in the rat, these receptors have been identified to be of great importance in the development of experimental arthritis however the particular mechanism is still unknown. The student work will include both in vitro and in vivo studies. Some important techniques are DNA typing, RNA expression assays, Cellular assays such as Flow-cytometry, Histochemistry, and ELISA. Primary cell cultures of macrophages and lymphocytes will be frequently used. A large focus will be on Phenotype assessment of genetically engineered mice either through macroscopic disease monitoring of experimental arthritis or directly by cellular assays. Entry requirements: We are looking for a highly motivated student with a background in immunology, medicine, molecular/cell biology, or physiology. An interest in genetics is an advantage. Good communication-skills in both written and spoken English are a requirement. Earlier lab-experience or experience with animal work is a plus. For details contact: Liselotte Backdahl liselotte.backdahl@ki.se
Laboratorieingenjör
Vi söker en laboratorieingenjör som kommer att arbeta med både murin och human genetik samt analyser av redox-system till Institutionen för medicinsk biokemi och biofyik (MBB). Tjänsten kommer placeras på avdelningen för medicinsk inflammationsforskning som leds av Professor Rikard Holmdahl på Institutionen för Medicinsk Biokemi och Biofysik. Vi söker nu dig som har en stark bakgrund inom både human- och musgenetik, immunologi, experimentell cellbiologi. Du förväntas kunna utföra både cellbiologiskt laboratoriearbete och bioinformatisk analys inkluderande human- och muringenetisk analys av komplexa sjukdomar.
Apply by 2013-04-05 Read more here
Postdoctoral position in mouse immunology and experimental atherosclerosis
A postdoctoral position is now open for a highly motivated scientist with a strong background in mouse immunology, and in vivo chronic inflammation disease models. The project focuses on investigating models for atherosclerosis and rheumatoid arthritis. The project will in particular investigate the role of newly positioned genetic polymorphism affecting regulatory macrophages.
Apply by 2013-03-03 Read more here
Project coordinator in Biochemistry
This position is open for a scientist experienced in protein biochemistry with an interest to assist in research project in an academic setting. The project involves expression and analysis of proteins and peptides in context of autoimmune diseases in experiment mouse models as well as in humans. A main project is to develop MHC class II based vaccines for treatment of rheumatoid arthritis. It will also involve the development of diagnostic solid phase assays using mini-proteins and peptides. Furthermore, basic identification and purification of various proteins identified through positional cloning in mouse and humans. Apply by 2012-12-02 Read more here
Postdoctoral position in mouse immunology
The project focuses on investigating regulatory effects of antigen presenting cells (macrophages, dendritic cells and B cells) on autoreactive T cell response in particular the role of reactive oxidative species as regulatory transmittors. The impact of the autoimmune regulation will be studied using models for rheumatoid arthritis. Apply by 2012-11-25 Read more here
Postdoctoral position in protein biochemistry and immunology
The project focuses on investigating the role of major histocompatibility complex II molecules in controlling the autoimmune response. It will involve work with recombinant protein expression both in bacterial and insect cells, functional and structural studies of proteins by biophysical approaches (such as surface plasma resonance, fluorescence spectroscopy, isothermal titration calorimetry,etc.), protein crystallization, antigen presentation assay and vaccination of animals in vivo. Apply by 2012-10-05 Read more here
Doctoral student position (Marie Curie) in experimental rheumatology
The PhD project is focused on investigating the effector mechanisms involving antibodies that can induce pathology in cartilage, as a first initial step towards development of arthritis. The project entails work on the cartilage biochemistry, cell biology, histopathology, experimental mouse work, molecular biology and antibody recognition of protein(s). Apply by 2012-09-20 Read more here
Postdoc in mouse autoimmunity and arthritis
The position is open for a highly motivated scientist with a background in immunology, knowledge of inflammatory disease models and good hands on experience with cellular immunology and experimental mouse technology. The project focuses on investigating a new model for rheumatoid arthritis with the possibility to reveal new T cell mediated pathogenic mechanisms related to redox regulation. Apply by 2012-08-31 Read more here
Postdoc in mouse B cell immunology
The position is open for a highly motivated scientist with a background in immunology, knowledge of inflammatory disease models and good hands on experience with cellular immunology and experimental mouse technology. The project focuses on investigating redox-regulation of B cell differentiation and autoimmunity. Apply by 2012-05-30 Read more here
Postdoc with experience in experimental immunology and in vivo imaging system
The position is open for a highly motivated scientist with a background in mouse immunology, knowledge of inflammatory disease models and good hands on experience with imaging technology. The project focuses on investigating various cellular infiltrations in target organs (e.g. joints) using in vivo imaging techniques and, visualizing reactive oxidative species production in rodents using different fluorescent probes. The impact of different cellular parameters on disease course will be studied using models of rheumatoid arthritis. Apply by 2012-06-03 Read more here
PhD position in mouse immunology
Apply by 2012-07-01
The department of Medical Biochemistry and Biophysics are looking for a PhD student that will work with Dr Kajsa Wing at the section of Medical Inflammation Research (http://www.inflam.mbb.ki.se/).
Work description:
We are looking for a highly motivated and inquisitive person that has the ambition to see the whole picture. The PhD project is focused on exploring a mouse model of adjuvant-induced arthritis in order to unravel new mechanistic insight in a chronic inflammatory disease. The project entails work on both innate and adaptive immune responses including lectin receptors, oxidative burst and T cell antigen reactivity. An interest in immunology is a must and an interest in glycobiology a bonus. The project includes breeding and maintaining of transgenic and congenic mouse strains for in vivo studies as well as for in vitro studies of primary cells.
The application is to be submitted on the KI NetRecruiter system.
Last day of application is July 1, 2012
Medical Inflammation Research (MIR) 